Side Effects

Side Effects

Isotretinoin is a systemic medication that belongs to retinoids (derived from vitamin-A).

This oral drug is used to treat certain severe skin inflammations such as nodular acne that is not responded to common treatment (creams, antibiotics, etc).

Acne problem is widely-spread in teenagers but some adults are also suffering from this skin disorder. Isotretinoin was used as a part of chemotherapy for some cancer forms.

Acne not only cause discomfort but also scars. Isotretinoin works by decreasing the sebum secretion that is associated with the acne formation.

The possible skin keratinization is also reducing by a positive Accutane Isotretinoin effect.

Treatment Course: The common treatment course of Isotretinoin lasts from 16 to 20 weeks.

As a rule, one course is enough for getting the expectable effect. The second course may be prescribed after the rest period if it is necessary.

It is important to take the full course of treatment even if you are satisfied with a skin condition. The completed course of treatment prevents possible risks of a relapse.

Patients should not miss the visits to a healthcare provider and be carefully monitored.

Isotretinoin in Use: The common form of Isotretinoin is oral capsules that should be taken by mouth once or twice a day according to the prescription.

Never change the doses without doctor’s approval and try not to miss them. The pills of Accutane (Isotretinoin) should be taken with food and be swallowed with a glass of liquid.

The dosage may be corrected by your doctor in case of side effects. It is normally if your skin condition gets worse during the first period of treatment.

The effect of Isotretinoin becomes evident after several weeks of treatment.

Isotretinoin and Pregnancy: When treating acne with Isotretinoin it is required to use certain birth control medication at least for a month before and after the course.

Isotretinoin should never be taken during the pregnancy as it is extremely harmful for an unborn baby. It is necessary to make two pregnancy tests and make sure that they are negative.

The question of future or present pregnancy should be discussed with a doctor prior the treatment. Isotretinoin is not recommended in breastfeeding because of the potential risks.

Warnings and Precautions:

  • Inform your doctor if you have an allergy to Isotretinoin and its components.
  • Notify your doctor about some inherited diseases that your relatives have (diabetes, mental illness, constant depressions or suicide thoughts) and such diseases as asthma, osteoporosis, anorexia nervosa, and any heart or liver diseases.
  • Sometimes Isotretinoin causes the changes in behavior, anger, sleepiness and insomnia, suicidal thoughts, psychosis or hallucinations. Your family and close people are supposed to take part in your treatment and support you morally. They should also control the changes of your mood and call for your doctor if it is necessary.
  • Isotretinoin may provoke some problems with your eyes such as feeling dryness or bad vision in darkness.

Side Effects

Isotretinoin can cause a number of side effects. Some of them are dangerous.

The following symptoms may occur:

  • dryness in eyes, nose and mouth;
  • changes in hair growth;
  • nosebleeds;
  • yellowing of the skin or eyes and changes in skin colour;
  • swellings;
  • skin peelings;
  • changes in voice;
  • flushing;
  • rectal bleeding;
  • bad healing of wounds;
  • nausea and vomiting;
  • headache;
  • chest and stomach pain;
  • seizures;
  • numbness;
  • dark urine;
  • ringing in ears;
  • fever and skin rush;
  • troubles with breathing.

The medication should be kept in a tightly closed container in a room temperature out of reach of children.